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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57fb4f48d1daf3b3cded1f68c5ae7e79ac38343bd6e417e6ab4f2979c537efbf' 
  AND token = 'iBooo+df8TLFAINMQC1+qanOLyO/bQ2rShqKxSlkLHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}