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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e0e7141f77bf9b3707aa32adc8936575012ec87dfd4aa19461f5de3a75f4fc' 
  AND token = 'opp/OCrbofjt921PfXjEpderiA7mtrIQ3sw+KTApWc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}