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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a80ad8cf4259c1dc86fe6e1f951e0dcdcca0e5286a1e2382ac67c0fc9073af' 
  AND token = 'K8oP183pu6pxVPf2QXji9jESW1yqiBJJCYJWXMTaWVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}