SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c48be8296cc321aec19482df4d72287d005cc8161c14c91522e8d86294811f' 
  AND token = 'PbVc5qFUgzgF0fRo0DAxB0ASkLW0T5+LQRdHdr0qcu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}