SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8943d5cf16b2f5826e78e863fa03ff55a060722e7f82ea037d30bb46c0ac02dd' 
  AND token = 'vQ4Nbk9Ozf+nPbkXfBnrrF+0h4A7m67dwnYPwUb7hSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}