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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171f3f2fbe516c88b38b9d636b498df18d2aad4637a008d00841bdd5a4aafa9f' 
  AND token = 'kgWuqQwRrzwYA4QhiUDD4EVzaWK5++qrp1lCd5Nyq74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}