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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a4b3180ed78661b1d5f2beae2f15774068ef619f876fbf1c0fddcf9bd5aeb9' 
  AND token = 'p0hP3bq/0CqYOMz8IxPXbLwS7mxazpIta57DWC/Y68g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}