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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393f4c3b5e4f4cb23e7e0ad1e720f09375ba8277b8d7948ac154531843a2b9f8' 
  AND token = 'DJ6MdRpRKBlDAWkF+iqT0+AsdSCjkqPTBmspRgF8CYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}