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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f154aebcc04b2f7a824e49df0bce133def715157d76eec2b039737d193a0db2' 
  AND token = 'upY9DKPcTH18M65SRbjG9+wHmEdXbAi7mvpyAmDdTtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}