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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4235b682b9aa07d9ba6925881571d1bae1c9a8e518eca3629c6e26aea83c32a1' 
  AND token = 'QckjGb7xfb2WJfxLURPk74bU0eYO28MlosOGaXFha3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}