SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b27cd0a629dbd4976f2402d235d46e2538f927d3a7059bfc3168c26ff424093' 
  AND token = '8cUOWcaxnKhLFBNyaLy3R0weZDc9pj39UDLjiopK8pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00154

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}