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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751b0b7593ef2ced45046ef58c1a6844b68ed9700445e331595cfbf8795acc54' 
  AND token = 'KPf+qOx6uRC4A4w7PMDmvK05tQ48IHiORSY7vKkg80E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}