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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e713aa138809b4cb0fd65c5295cabb714d079730b9ced1c9392988c74de229' 
  AND token = 'NgPxAHHAPTdOwpWGFHD6gpxr3IIcm5tF8Qp7/+zXduA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}