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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413a78c8a51c1512e649a7660d631a2dd28d457f53de4300e5e6c038bcada49c' 
  AND token = '9YZwNa8tjO0tyWiN2TmD2xmbRLDrmkT598kcDEPaGS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}