SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6709ac99fbf5c57ada58506c1ba17d1f61860b64e58f0f49454e64c4091d48' 
  AND token = 'V+REKCpKkhBTxQronYtRikWAI9lA4/56yV8MLp18Dn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}