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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0182623c0bb818b708db1e2a9864a23293c33c3d201fe205a16f8f829ddd940' 
  AND token = '2CQGDBc6rZ1mfOIGZwlyDkrqCsQGkXAbQFtvx7ALWN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}