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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798ac80fe0367a2a39a5b34a8c60e51fc081de55999fbe0a2d87e9f00450b304' 
  AND token = 'tuyKEdhFpk+IAJuMRZczuOfGM12Hf1SSfKT4vC6cPns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}