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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ea7507f1afe66690f79c6d2be2deb94bbe108d11213e6d8dfe86e029b6ba72' 
  AND token = 'gxZ9yWW26VW7cWLsiVw3XPJinZKF53whv4EPdGBKaOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}