SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e932743960fee9892a9ceee27ce751f06cf75a9880181bc23697a72ebd09548a' 
  AND token = 'LsH2mciZ1+3l5haIXYytT8a9T2z60Laq7mcb821udPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}