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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e16a41464e57b44d1c83d84de64a9d008399b323de13719d9c50ee86c0ae2bd' 
  AND token = 'ShUTtZ9iM41w+lRlZs0LWhSz791t0BGHC8GbFkaFzv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}