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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292247bd6cd0fce0cd5967fa1b77d555e0293e73b85ca310d08d0f524d5dbc43' 
  AND token = 'ZmVpMn1br8rNAmJSbRhYa7Q6/Qc/1Qu46+3PwNTpeYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}