SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1fe08eaaefb04cb580824c5c07b5dd371930926b813615360b97e0ec7b73e4' 
  AND token = 'SwydVBCxCA6bnJ+WQTpKSIJlTmqOi8/VD79qRgxOyr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}