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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18053d99a40045ca91f1a78167b817612721d88e14e03d609b79ca2985846722' 
  AND token = 'cREVP/xAxJPj7i75JnfOEPS5Qz+lfFEPsweoscaUcIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}