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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620d20410ee9a249fe0cf39ddf4975faa8a098cabdf284216b085f75c51c6cd7' 
  AND token = 'MlNlx9GN04YElVzfbJVq1MN2Kdbrf6vWzRkN3k9AgiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}