SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec537883bca6620fc3b7453dd8d4faf59aafb8701bb0f768e53286610aade73' 
  AND token = 'A9x3LfkNhs2NmsM6j4d+eyY7sf/nc5pK8/GGSw++YxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}