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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c678542c263f087717c4dcfb0f3efa166c6f1d2feb1dc5adea8ded7ff1272beb' 
  AND token = '2tz8PRCkBZFIB3+JdW6kA9gcz/gj1ihIrHQpwHN1ArQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}