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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783dc0de319ddce4dc1378f54d3c4c151e54b296b56b6755404b8db9002ce231' 
  AND token = 'Ek+3Z+sr+kpy8iQDPXZ1wobRGIzRhFNGUErQXpjbuPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}