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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39fde60d2b998a8f72bd0619220764c243f2ddbc807dfb8f40df7560b064f789' 
  AND token = 'C1sSZfSVfDDaByeBvi8KVVBp+AmqWSzoBYs97E+Qcog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}