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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38f2f987eba270cd1bed882c419acf77e818e367248b348e506271579218ac0' 
  AND token = 'S5gUHSTBYhRzh+N+REpsdAMdGqWsqe3JBW6xSrN8raI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}