SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783bc5bafad0b397c0b58da557321bf36d20c5867900257438c12cf5ccbbd95d' 
  AND token = 'fR7ztRhy30np3G5RO1RLxpb49MLqGahS1rtJb1TPoWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}