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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337998171910a96f50f7a5a8976b0279d75a165f582816a705ae9ec62ea55dbd' 
  AND token = 'u/NvKCT+cx1hmeTnJSli5BLnrK2mJaW7d/ac6dGQjIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}