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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c541e482da5cc5b9504c57c24f0bd3e3ff381a5717c05c92a8b5628a4534f515' 
  AND token = '0E/loBsLI0lnJ3ll9UuSYSd4+YryBkmfxWviVLdWFsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}