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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4053d3b8da95fd5fdc07530de0b3f3be73704f278366a366208be4bf82a903ad' 
  AND token = 'd0e0H9eLQSq6YHZxR9hw8Krc8qLEU9tUQb2wKRlXoC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}