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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf35953d91f668caca49554bca1392d904723e36b151683320e8da9a4fff149' 
  AND token = '+b9Bii9Aw7nhd2xirVt51EeZsWfMZZ7I0ukKDYhmB8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}