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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1ca3619631701d4e8b8d8f78c3c364e66154d1f9f93c867e629874f36877c4' 
  AND token = 'uLAiCNVllNp+a6xtIZuWTk+85b0bWrYwvrTyIFWBex8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}