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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ac76418b6661825a96ce465ebd34879e02e1df64c102547fb50a7c88db9d1d' 
  AND token = 'xHI3zN6dmUC4w4l+k2f/dTsNBiV+facBPKEKpZN7vZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}