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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c36294212cd29a0f964822683721877b43468f7c6a0fb637843e90c3bb34ba6' 
  AND token = 'tJHwNgdp5cuyPqY4pEjg83i6TPIOzEJ2KvzmZ85iqHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}