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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4cffea4b603a86fd1b5c79f44876b6e06cfa4cd962061c3d78ce5aac318bdd' 
  AND token = 'uHXSKN9lJhm5H0Smn0mShqHM4MJGQmohIND0ys7kj3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}