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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3453a58ca3b3db206bacbe5fd1babd1bf10d3f38f7a9c60a20fc52c12726e2c' 
  AND token = '8d5uenfsR8nYVtPU0QQ9zbDJK1bZRV+QnjTLJHpaPbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}