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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e080add353395d4189b50e9354eb8902510238f7936d8d4306f73384c0cd61c7' 
  AND token = 'ELjgHiElH1qIKLwus+XIYDbmp2geoH6obnJJCqL2tW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}