SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448e2d02a5e341afa38825483b340120bffb2bf782af4c07e131eb054957d480' 
  AND token = 'W4iP1XaBkrkcOMBKOcyGvVvH5qXJuHtdXuSa630bxWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}