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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868d49aac777cd1524fc63a6c0b3c4a0d36106395c65af605d35dd1823d23af1' 
  AND token = '5xgTsvz9l4AOzcgupSvccF9zOWOYSSQd4F9T/ykhAwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}