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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '892451b99ac1fb0224560451f33d38d3cc1642fc8f6d25df5bc787a782bebe21' 
  AND token = '11IGtHLm0GxS8R/fx9BCytM64SNVCYnhAArOuuaftJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}