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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f4815efad05a4a6eccf35cc52da7ffbb3ab921bacaf31117526f762d68760f' 
  AND token = '+sSQWsg2Is+0SmiJcs8DjvdOvb/G/ApUyCJOAfK4Qrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}