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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99243a28511c419042a4254b38d383e2b4194b47e5d25cbd5037d5b6baafd59b' 
  AND token = '1WvJaUddfluufmInKbAx1JO9PXBq5O9QlbNkCFYdq/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}