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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc2282d953a90a987a55d7ca314e8d3d9c2a160164afdc3a4d7dc4ce564dc1b0' 
  AND token = 'Qfxbe4N6n6B2gicOX7Xo5L+3HhrW4L3a+oTVzYf5ZBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}