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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc4d7997bed430031e0157e2d288d5b5e1fda95cf84b2b111a960d04e3dfbee' 
  AND token = 'Bm0KjUjT4Tx1xGRl5GcMg+miAMi7Ze56EQqhBOFiBaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}