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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27470e19a46bb612a098fc9332e708c55b5195d035477cba70f12853b67dfb2' 
  AND token = 'VzOggfTWW0bzs2lU1Y4MPxZn50s0nN3MGp5X0tdK6WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}