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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9395066c267d5c0bfe830c51743cb71151cd56faea66c2df8e17b0456b7f1e0' 
  AND token = '4uldD/cK3e1TwF0xu+GVaV6i68cB6dzT+hsI7jZn7iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}