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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec289b5201849e321cbbdf1d05d217a99dd339cc51a609d0177979e3de6fbf8' 
  AND token = 'Cl+QFQfd9Ppfng6bOLupzxYtwHRv71Rv4tEZYhT30lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}